Endometriyum kanseri\u00a0 endometriyumdan (rahmin her adet d\u00f6neminde d\u00f6k\u00fclen i\u00e7 tabakas\u0131) kaynaklan\u0131r. Endometriyum kanseri, kad\u0131n \u00fcreme sisteminde en s\u0131k g\u00f6r\u00fclen kanser tipidir. \u00a0T.C. Sa\u011fl\u0131k Bakanl\u0131\u011f\u0131 Kanser Dairesi verilerine g\u00f6re 2008 y\u0131l\u0131nda endometriyum kanserinin g\u00f6r\u00fclme s\u0131kl\u0131\u011f\u0131 y\u00fcz binde 7.9\u2019dur. Yine Globacan (WHO) verilerine g\u00f6re 2008 y\u0131l\u0131nda T\u00fcrkiye\u2019de 1937 kad\u0131n\u0131n endometriyum kanseri te\u015fhisi ald\u0131\u011f\u0131\u00a0 ve 519 kad\u0131n\u0131n endometriyum kanserinden \u00f6ld\u00fc\u011f\u00fc tahmin edilmektedir.<\/p>\n
Endometriyum kanseri, rahim i\u00e7 zar\u0131ndan (tabakas\u0131ndan) (gebelik s\u0131ras\u0131nda bebe\u011fin b\u00fcy\u00fcd\u00fc\u011f\u00fc, \u00a0i\u00e7i bo\u015f, armut \u015feklinde organ) kaynaklan\u0131r ve rahim kanserlerinin b\u00fcy\u00fck bir b\u00f6l\u00fcm\u00fcn\u00fc olu\u015fturur. Rahim kas ve destekleyici ba\u011f dokusundan (stroma) ba\u015fayan ve \u00e7ok nadir olan kanserler rahim sarkomlar\u0131 olarak isimlendirilir.<\/p>\n
Rahim kanseri, T\u00fcrkiye\u2019de en s\u0131k g\u00f6r\u00fclen jinekolojik kanserdir. Kad\u0131n kanserleri s\u0131ralamas\u0131nda ise d\u00f6rd\u00fcnc\u00fc s\u0131kl\u0131kta g\u00f6r\u00fcl\u00fcr. Rahim kanseri iki b\u00fcy\u00fck guruba kategorize edilebilir: rahim i\u00e7 mukozas\u0131ndan (endometriyum) kaynaklanan ve karsinom olarak adland\u0131r\u0131lan kanserler ve sarkom olarak adland\u0131r\u0131lan rahim kaslar\u0131n\u0131n kanseridir. Sarkomlar nadir t\u00fcm\u00f6rlerdir.\u00a0 Rahim i\u00e7 mukozas\u0131ndan k\u00f6ken alan kanserlere g\u00f6re daha \u00e7ok daha az g\u00f6r\u00fcl\u00fcrler. A\u015fa\u011f\u0131da verilen bilgiler, kad\u0131nlarda daha s\u0131k g\u00f6r\u00fclen endometriyal kanser tipi i\u00e7indir.<\/p>\n
Endometrial kanserler, rahimin i\u00e7 mukozas\u0131ndan ba\u015flar. Rahim, kad\u0131nlar\u0131n \u00fcreme sa\u011fl\u0131\u011f\u0131nda, \u00f6zellikle de gebe kalabilece\u011fi y\u0131llarda \u00f6nemli rol oynar. Hamile olma durumunda, d\u00f6llenmi\u015f yumurtan\u0131n yerle\u015febilece\u011fi ve bebe\u011fin geli\u015fece\u011fi yerdir.\u00a0 Kad\u0131nlar\u0131n adet siklus veya periyodunda, rahim mukozal tabakas\u0131 kanama \u015feklinde d\u00f6k\u00fcl\u00fcr.<\/p>\n
Endometriyal kanseri tam olarak neyin tetikledi\u011fi bilinmemektedir. Fakat; ya\u015f, obesite, hormonal bozukluklar ve genetik yatk\u0131nl\u0131k risk fakt\u00f6rleridir. Endometriyal kanser taramas\u0131 i\u00e7in veya tamamen \u00f6nlemek i\u00e7in hi\u00e7 yol yoktur.\u00a0 Bir \u00e7ok kad\u0131nda hastal\u0131\u011f\u0131n erken d\u00f6neminde \u015fikayetler olur. Endometriyal kanserin en s\u0131k \u015fikayeti menopoz sonras\u0131 kanamad\u0131r.\u00a0 Baz\u0131 gen\u00e7 kad\u0131nlar\u0131n, normal periyotlar\u0131nda de\u011fi\u015fiklik olacakt\u0131r. Sonu\u00e7ta, rahim kanseri bir\u00e7ok vakada erken d\u00f6nemde tespit ve tedavi edilir.<\/p>\n
Menopoz sonras\u0131 d\u00f6nemde vajinal kanama olarak tan\u0131mlanan postmenopozal kanama rahim kanserinin en s\u0131k belirtisidir. Postmenopozal d\u00f6nemdeki kanama, damla \u015feklinde kanamdan \u00e7ok a\u011f\u0131r vajinal kanama \u015feklinde herhangi bir miktarda olabilir. Kanama do\u011fal menopoz s\u00fcrecinin herhangi bir zaman\u0131nda meydana gelebilir. Meydana geli\u015f zaman\u0131ndan veya miktar\u0131ndan ba\u011f\u0131ms\u0131z olarak, postmenopozal kanama hi\u00e7bir zaman normal bir olay gibi d\u00fc\u015f\u00fcn\u00fclmemelidir. Menopoz \u00f6ncesi d\u00f6nem i\u00e7inde, d\u00fczensiz veya yo\u011fun menst\u00fcrel kanama \u00e7o\u011funlukla kanser d\u0131\u015f\u0131 nedenlerle a\u00e7\u0131klanmas\u0131na ra\u011fmen endometrial kanserin bir belirtisi olabilir. Endometrial kanserin daha nadir bulgular\u0131 pelvik a\u011fr\u0131, \u015fi\u015fkinlik ve krampt\u0131r.<\/p>\n
Rahim kanseri endometrium dokusunda geli\u015ftikten sonra kad\u0131n \u00fcreme sisteminin di\u011fer organlar\u0131na da yay\u0131lma e\u011filimindedir. \u0130lk \u00f6nce rahim a\u011fz\u0131 (serviks), t\u00fcpler ve yumurtal\u0131klara do\u011fru yay\u0131l\u0131r. Daha ilerlemi\u015f hastal\u0131k durumlar\u0131nda lenfatik damarlar arac\u0131l\u0131\u011f\u0131 ile v\u00fccudun di\u011fer b\u00f6l\u00fcmlerine atlar. Bir kanserin lenf veya kan yoluyla yay\u0131lmas\u0131 olay\u0131na \u201cmetastas\u201d denir. Evrelendirme hastal\u0131\u011f\u0131n ne kadar yay\u0131ld\u0131\u011f\u0131n\u0131n anla\u015f\u0131labilmesi i\u00e7in yap\u0131lan i\u015flemdir. Endometrium kanserinde evrelendirme cerrahi olarak yap\u0131l\u0131r. Evreleme, tedav\u0131 se\u00e7imi i\u00e7in \u00f6nemli bir kriterdir. Endometrium kanser\u0131nde en yayg\u0131n kullan\u0131lan evreleme FIGO evrelendirme sistemidir. Kabaca t\u00fcm kanserler hastal\u0131\u011f\u0131n yayg\u0131nl\u0131\u011f\u0131na g\u00f6re 4 evreye ayr\u0131l\u0131r. Endometrium kanserinde hastal\u0131k sadece uterusun korpusuna (g\u00f6vdesine) yerle\u015fmi\u015f ise evre I, rahim a\u011fz\u0131na yay\u0131lm\u0131\u015f ise evre II, rahmin d\u0131\u015f\u0131na \u00e7\u0131km\u0131\u015f ancak sadece rahme kom\u015fu organlara (t\u00fcpler, yumurtal\u0131klar) veya b\u00fcy\u00fck damarlar etraf\u0131ndaki bezelere (lenf bezleri) yay\u0131lm\u0131\u015fsa evre III, daha uzak organlara (\u00f6rne\u011fin kar\u0131n i\u00e7indeki di\u011fer oraganlara akci\u011fere vs) yay\u0131lm\u0131\u015fsa evre IV olarak hastal\u0131k tan\u0131mlan\u0131r. Bu evreler ayr\u0131ca endi i\u00e7lerinde de hastal\u0131\u011f\u0131n yayg\u0131nl\u0131\u011f\u0131n\u0131n durumuna g\u00f6re alt gruplara ayr\u0131l\u0131r.<\/p>\n
Evreleme sonras\u0131 doktorunuza hastal\u0131\u011f\u0131n\u0131z\u0131n evresini anlayaca\u011f\u0131n\u0131z \u015fekilde anlatmas\u0131n\u0131 s\u00f6yleyiniz.<\/p>\n
Tedavi kesinlikle kanserle ilgilenen jinekologlar (jinekolog onkolog) taraf\u0131ndan planlan\u0131p yap\u0131lmal\u0131d\u0131r. Endometrium kanseri tan\u0131s\u0131 konulduktan sonra ba\u015fl\u0131ca 4 tedavi se\u00e7ene\u011fi vard\u0131r. Cerrahi, radyoterapi, hormonal tedavi ve kemoterapi. Cerrahi tedavi bir \u00e7ok endometrium kanserinde ana ve ilk tedavi y\u00f6ntemidir. Ancak bazen bu tedavi y\u00f6ntemlerinin kombinasyonu kullan\u0131labilir. Tedavi se\u00e7imi kanserin evresine g\u00f6re de\u011fi\u015fir.<\/p>\n
Rahim kanserinde \u00a0ameliyat sonras\u0131nda kemoterapi veya radyoterapi uygulan\u0131p uygulanmamas\u0131na patoloji raporuna, t\u00fcm\u00f6r\u00fcn histolojik tipi ve b\u00fcy\u00fckl\u00fc\u011f\u00fcne , rahim duvar\u0131na olan derinli\u011fine yay\u0131lmas\u0131na \u00a0ve lenf bezlerine metastaz yap\u0131p yapmamas\u0131na g\u00f6re karar verilir.<\/p>\n","protected":false},"excerpt":{"rendered":"
Endometriyum kanseri\u00a0 endometriyumdan (rahmin her adet d\u00f6neminde d\u00f6k\u00fclen i\u00e7 tabakas\u0131) kaynaklan\u0131r. Endometriyum kanseri, kad\u0131n \u00fcreme sisteminde en s\u0131k g\u00f6r\u00fclen kanser tipidir. \u00a0T.C. Sa\u011fl\u0131k Bakanl\u0131\u011f\u0131 Kanser Dairesi verilerine g\u00f6re 2008 y\u0131l\u0131nda endometriyum kanserinin g\u00f6r\u00fclme s\u0131kl\u0131\u011f\u0131 y\u00fcz binde 7.9\u2019dur. Yine Globacan (WHO) verilerine g\u00f6re 2008 y\u0131l\u0131nda T\u00fcrkiye\u2019de 1937 kad\u0131n\u0131n endometriyum kanseri te\u015fhisi ald\u0131\u011f\u0131\u00a0 ve 519 kad\u0131n\u0131n endometriyum […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-456","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/profdrahmetkale.com\/index.php\/wp-json\/wp\/v2\/pages\/456","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/profdrahmetkale.com\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/profdrahmetkale.com\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/profdrahmetkale.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/profdrahmetkale.com\/index.php\/wp-json\/wp\/v2\/comments?post=456"}],"version-history":[{"count":1,"href":"https:\/\/profdrahmetkale.com\/index.php\/wp-json\/wp\/v2\/pages\/456\/revisions"}],"predecessor-version":[{"id":457,"href":"https:\/\/profdrahmetkale.com\/index.php\/wp-json\/wp\/v2\/pages\/456\/revisions\/457"}],"wp:attachment":[{"href":"https:\/\/profdrahmetkale.com\/index.php\/wp-json\/wp\/v2\/media?parent=456"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}